Factory Supply High Quality Letermovir Powder

• CAS No.: 917389-32-3
• Formula: C29h28f4n4o4
• EINECS: 200-001-8
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Pharma Grade
• Model NO.: 917389-32-3
• Colour: White
• Shelf Life: 24 Months
• MOQ: 10g
• Lead Time: 1-3 Working Days
• Payment: Tt/Bank Transfer/Western Union
• Transport Package: 25kgs/Drum
• Specification: 99%
• Trademark: ZB
• Origin: China
• Production Capacity: 100000kgs/Month

Product Description

                                                      LeterMovir

Product Name	LeterMovir
Category	Plant Extracts
Analysis	HPLC
Storage	Keep in cool and dry place, well-closed, away from moisture or direct sunlight.

Letermovir (aic246, mk-8228) is a novel anti CMV compound, which targets the virus terminal enzyme complex and is also active for viruses resistant to DNA polymerase inhibitors.

AIC246 was able to prevent viral replication without inhibiting the synthesis of progeny CMV DNA or the synthesis of viral proteins. AIC246 is currently one of the Chemicalbook effective anti-HCMV (cytomegalovirus) reagents, its EC50 value in cells is about 5nM, and the selectivity index is more than 15000.


In the mouse transplanted tumor model, the experimental mice treated with AIC246 showed a dose-dependent decrease in HCMV titer in transplanted cells compared with the control mice treated with placebo.

 

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