| CAS No.: | 124-20-9 |
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| Formula: | C7h19n3 |
| EINECS: | 204-689-0 |
| Type: | Pharmaceutical Intermediates |
| Appearance: | Powder |
| Quality: | Pharma Grade |
| Samples: |
Sample is free, only shipping cost
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| Customization: |
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Suppliers with verified business licenses
Audited Supplier 
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Product Name
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Spermidine |
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Category
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Healthcare products
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Analysis
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HPLC
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Storage
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Keep in cool and dry place, well-closed, away from moisture or direct sunlight.
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Spermidine is a naturally occurring polyamine compound that is found in all living cells, including plants, animals, and microorganisms. It is synthesized from the amino acid L-ornithine through a series of enzymatic reactions. Spermidine is involved in various biological processes and has been found to have potential health benefits.
Here are some key points about spermidine:
Role in Cellular Function: Spermidine plays essential roles in cell growth, division, and differentiation. It is involved in DNA and protein synthesis, cell signaling, and the regulation of gene expression. Spermidine also helps stabilize proteins and nucleic acids, protecting them from damage.
Autophagy Induction: One of the well-known functions of spermidine is its ability to induce autophagy. Autophagy is a cellular process involved in the degradation of damaged or unnecessary cellular components. It helps to remove cellular waste and recycle cellular materials, promoting overall cellular health and longevity.
Anti-Aging Effects: Spermidine has gained attention for its potential anti-aging properties. Studies have shown that spermidine supplementation in model organisms like yeast, nematodes, flies, and mice can extend lifespan and improve healthspan. Its ability to induce autophagy and enhance cellular recycling processes is believed to contribute to its anti-aging effects.
Cardiovascular Health: Some research suggests that spermidine may have cardio-protective effects. It may help lower blood pressure, reduce oxidative stress, improve heart function, and lower the risk of cardiovascular diseases.
Neuroprotection: Spermidine has also shown potential neuroprotective effects. It may help protect neurons from oxidative stress, reduce neuroinflammation, and promote neuronal survival. Spermidine's ability to induce autophagy may be particularly beneficial in reducing the accumulation of abnormal protein aggregates, which are associated with neurodegenerative diseases.
Dietary Sources: Spermidine can be obtained from various dietary sources, including wheat germ, soybeans, mushrooms, corn, and some aged cheeses. The levels of spermidine in these foods can vary greatly.
Supplementation: Spermidine is also available as a dietary supplement. Spermidine supplements typically come in the form of capsules or powder. If considering supplementation, it is recommended to consult with a healthcare professional for guidance on appropriate dosage and to ensure it is suitable for individual needs and health conditions.
Spermidine is a naturally occurring polyamine compound found in cells and tissues of both plants and animals. It plays various roles in cellular function and has been studied for its potential health benefits.
Cellular Function: Spermidine is involved in numerous cellular processes, including cell growth, proliferation, and differentiation. It helps support DNA and protein synthesis, cell signaling, and regulation of gene expression.
Autophagy Induction: One of the most well-studied functions of spermidine is its ability to induce autophagy, a process where the body removes damaged or unnecessary cellular components, recycling them for energy and building blocks. This can help maintain cellular homeostasis and promote cellular health.
Anti-Inflammatory Effects: Spermidine has shown potential anti-inflammatory effects. It may help regulate the immune response and reduce inflammation, which can be beneficial in various inflammatory conditions.
Cardiovascular Health: Preliminary research suggests that spermidine may have cardioprotective effects. It has been associated with improved heart function, reduced risk of cardiovascular diseases, and increased lifespan in animal studies.
Neuroprotection: Spermidine has shown neuroprotective effects in various studies. It may help protect against neurodegenerative diseases by promoting autophagy, reducing oxidative stress, and enhancing cellular resilience.
Anti-Aging Effects: Emerging evidence suggests that spermidine may have anti-aging properties. It has been associated with increased lifespan and improved healthspan in model organisms and has shown potential in reducing age-related memory decline in animal studies.
Spermidine can be obtained through dietary sources, such as wheat germ, soybeans, mushrooms, and aged cheese. However, it is also available as a dietary supplement in various forms. It is essential to note that more research is still needed to fully understand the mechanisms and potential benefits of spermidine supplementation, and individual responses may vary.
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